Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790343 | 0.88 | CYP2E1 (0.39) | POLBCHRM5HTR6TSHRCNR2 | |
| SCHEMBL4792179 | 0.86 | CYP2A6 (0.36) | POLBCHRM5PTGS2TSHRCNR2 | |
| SCHEMBL1580390 | 0.83 | TSHR (0.39) | POLBPTGES2CHRM5PTGS2HTR6 | |
| SCHEMBL4793066 | 0.82 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL4791377 | 0.82 | GBA1 (0.38) | HTR6CNR2NAPRTSMN1; SMN2 | |
| SCHEMBL3906007 | 0.80 | TSHR (0.42) | TSHR | |
| SCHEMBL1278515 | 0.79 | NAMPT (0.40) | HTR6TSHRGAAGFERSMN1; SMN2 | |
| SCHEMBL1278681 | 0.78 | TACR1 (0.38) | TSHRGAAGFERSMN1; SMN2 | |
| SCHEMBL4793151 | 0.78 | PTGES2 (0.35) | POLBPTGES2CHRM5PTGS2HTR6 | |
| Fumaric Acid SCHEMBL1278086 | 0.77 | HDAC1 (0.36) | POLBTSHRGAAGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919865-A1 | 1-HETEROCYCLYLSULFONYL, 2-AMINOMETHYL, 5- (HETERO-) ARYL SUBSTITUTED 1-H-PYRROLE DERIVATIVES AS ACID SECRETION INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026916-A1 | 1-HETEROCYCLYLSULFONYL, 2-AMINOMETHYL, 5- (HETERO-) ARYL SUBSTITUTED 1-H-PYRROLE DERIVATIVES AS ACID SECRETION INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |