Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853119 | 0.81 | CASP1 (0.47) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL2853071 | 0.77 | CASP1 (0.55) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL2851318 | 0.75 | KDM4E (0.52) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL2853271 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL13499267 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL30040702 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL2854724 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL14535566 | 0.70 | KDM4E (0.44) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL2849135 | 0.69 | CASP1 (0.56) | ALDH1A1KDM4EL3MBTL1TDP1LMNA | |
| SCHEMBL5091732 | 0.69 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924558-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007032016-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | disclosed |