Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124024 | 1.00 | KMT2A (0.44) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL2124019 | 1.00 | KMT2A (0.44) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL2571856 | 0.92 | CASP1 (0.44) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL2571851 | 0.92 | CASP1 (0.44) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL480580 | 0.92 | RXFP1 (0.48) | KMT2AMEN1RXFP1L3MBTL1POLB | |
| SCHEMBL480582 | 0.92 | RXFP1 (0.48) | KMT2AMEN1RXFP1L3MBTL1POLB | |
| SCHEMBL2119697 | 0.88 | KMT2A (0.43) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL2572117 | 0.87 | KMT2A (0.40) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL479766 | 0.87 | KMT2A (0.40) | KMT2ACTDSP1CASP1MEN1BACE1 | |
| SCHEMBL2119693 | 0.87 | KMT2A (0.40) | KMT2ACTDSP1CASP1MEN1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |