SCHEMBL4794080

SCHEMBL4794080

CC(=O)OCCNc1c(C)c(C)nc(Oc2ccccc2)c1N.CC(=O)OCCn1c(C)nc2c(Oc3ccccc3)nc(C)c(C)c21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
FAAH O00519 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
SLC18A3 Q16572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337848 0.88 SLC18A3 (0.37) KDM4EALDH1A1KMT2ASLC18A3
SCHEMBL5340227 0.87 KDM4E (0.42) KDM4ERECQLALDH1A1KMT2A
SCHEMBL4793912 0.84 SLC18A3 (0.35) KDM4EALDH1A1KMT2ASLC18A3
SCHEMBL4795253 0.75 ALDH1A1 (0.51) KDM4EALDH1A1
SCHEMBL1232835 0.74 ALDH1A1 (0.36) ALDH1A1KMT2A
SCHEMBL4772034 0.73 HTR7 (0.42) ALDH1A1
SCHEMBL4793644 0.73 ALDH1A1 (0.35) ALDH1A1KMT2A
SCHEMBL28753431 0.72 TOP2A (0.37) RECQLFAAHALDH1A1KMT2A
SCHEMBL1232939 0.72 TOP2A (0.37) KDM4ERECQLALDH1A1KMT2A
SCHEMBL4835830 0.72 KDM4E (0.39) KDM4ERECQLALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513524-A4 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2008-09-03 EP disclosed
EP-1513524-A2 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M Innovative Properties Company (US) 2005-03-16 EP disclosed
WO-2003103584-A2 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-12-18 WO disclosed