Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794280 | 1.00 | DGAT1 (0.48) | DGAT1CA12CA2CA14 | |
| SCHEMBL27575604 | 0.85 | DGAT1 (0.48) | DGAT1CA12CA2CA14 | |
| SCHEMBL28842397 | 0.85 | DGAT1 (0.48) | DGAT1CA12CA2CA14 | |
| SCHEMBL27966695 | 0.85 | DGAT1 (0.48) | DGAT1CA12CA2CA14 | |
| SCHEMBL27703128 | 0.85 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL27706532 | 0.84 | CYP4F2 (0.37) | DGAT1 | |
| SCHEMBL27801427 | 0.83 | DGAT1 (0.50) | DGAT1CA12CA2CA14 | |
| SCHEMBL11126560 | 0.82 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL5027322 | 0.82 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL27481413 | 0.82 | DGAT1 (0.46) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078116-A9 | P38 INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC (US) | 2008-09-12 | — | — | WO | disclosed |