SCHEMBL5027322

SCHEMBL5027322

COC(=O)C(N)(CCCN)C(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.46
ODC1 P11926 2/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19065775 0.95 DGAT1 (0.44) DGAT1TDP1
SCHEMBL3294151 0.93 DGAT1 (0.38) DGAT1ODC1KDM4ELMNAMAPT
SCHEMBL7802855 0.87 DGAT1 (0.36) DGAT1ODC1KDM4ELMNAMAPT
SCHEMBL28262864 0.86 DGAT1 (0.46) DGAT1LMNAMAPTTDP1MAOA
SCHEMBL27481413 0.86 DGAT1 (0.46) DGAT1TDP1MAOAMAOB
SCHEMBL587833 0.86 PAOX (0.36) DGAT1ODC1LMNATDP1MAOA
SCHEMBL20496960 0.86 PAOX (0.36) DGAT1ODC1LMNATDP1MAOA
SCHEMBL9196272 0.86 PAOX (0.36) DGAT1ODC1LMNATDP1MAOA
SCHEMBL569250 0.85 DGAT1 (0.45) DGAT1TDP1MAOAMAOB
SCHEMBL2270874 0.84 ODC1 (0.42) DGAT1ODC1KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed