Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162325 | 0.90 | ALDH1A1 (0.56) | ALDH1A1PKMLMNAKMT2AACE | |
| SCHEMBL10703610 | 0.78 | ALDH1A1 (0.36) | ALDH1A1PKMLMNACA12CA1 | |
| SCHEMBL5705701 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1PKMLMNACA12CA1 | |
| SCHEMBL14249718 | 0.76 | ALDH1A1 (0.43) | ALDH1A1PKMLMNAKMT2ACA12 | |
| SCHEMBL12478991 | 0.76 | ALDH1A1 (0.43) | ALDH1A1PKMLMNAKMT2ACA12 | |
| SCHEMBL9453802 | 0.76 | ALDH1A1 (0.53) | ALDH1A1PKMKMT2AACEMME | |
| SCHEMBL2813031 | 0.76 | ALDH1A1 (0.53) | ALDH1A1PKMLMNAKMT2ACA12 | |
| SCHEMBL18137281 | 0.75 | MAPT (0.42) | ALDH1A1PKMKMT2AACEMME | |
| SCHEMBL6794551 | 0.75 | ALDH1A1 (0.42) | ALDH1A1PKMLMNACA12CA1 | |
| SCHEMBL542270 | 0.73 | ALDH1A1 (0.50) | ALDH1A1PKMLMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089256-A2 | POLYMERIC THERAPEUTICS | CAPPELLA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |