Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794872 | 0.90 | ALDH1A1 (0.47) | ALDH1A1PKMACEMMEKMT2A | |
| SCHEMBL9453802 | 0.84 | ALDH1A1 (0.53) | ALDH1A1PKMACEMMESLC1A2 | |
| SCHEMBL3505155 | 0.81 | ALDH1A1 (0.58) | ALDH1A1PKMMMESLC1A2KMT2A | |
| SCHEMBL18137281 | 0.80 | MAPT (0.42) | ALDH1A1PKMACEMMEKMT2A | |
| SCHEMBL24300565 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PKMMMESLC1A2KMT2A | |
| SCHEMBL2332165 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PKMMMESLC1A2KMT2A | |
| SCHEMBL698898 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PKMMMESLC1A2KMT2A | |
| SCHEMBL604671 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PKMMMESLC1A2KMT2A | |
| SCHEMBL73144 | 0.78 | ALDH1A1 (0.54) | ALDH1A1PKMMMESLC1A2KMT2A | |
| SCHEMBL10421278 | 0.78 | ALDH1A1 (0.54) | ALDH1A1PKMMMESLC1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608390-A1 | TUMOUR SENSITISATION TO CHECKPOINT INHIBITORS WITH REDOX STATUS MODIFIER | Cancer Research Technology Limited (GB) | 2025-09-03 | — | — | EP | disclosed |
| US-20250243168-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | THE WISTAR INST (US) | 2025-07-31 | — | — | US | disclosed |
| US-12281084-B2 | Acetyl-CoA synthetase 2 (ACSS2) inhibitors and methods using same | THE WISTAR INSTITUTE (US) | 2025-04-22 | — | — | US | disclosed |
| WO-2024089418-A1 | TUMOUR SENSITISATION TO CHECKPOINT INHIBITORS WITH REDOX STATUS MODIFIER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-05-02 | — | — | WO | disclosed |
| US-20220281826-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | THE WISTAR INSTITUTE | 2022-09-08 | — | — | US | disclosed |
| EP-0698089-B1 | NUCLEIC ACID ENCODING AMP-ACTIVATED PROTEIN KINASE | ASTRAZENECA AB (SE) | 2007-03-14 | — | — | EP | disclosed |
| EP-1573061-A4 | MULTIPLEXED IMMUNOHISTOCHEMICAL ASSAYS USING MOLECULAR TAGS | ACLARA BIOSCIENCES INC (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1573061-A1 | MULTIPLEXED IMMUNOHISTOCHEMICAL ASSAYS USING MOLECULAR TAGS | Aclara BioSciences, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004061131-A1 | MULTIPLEXED IMMUNOHISTOCHEMICAL ASSAYS USING MOLECULAR TAGS | ACLARA BIOSCIENCES, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2002097112-A2 | CATALYTIC AMPLIFICATION OF MULTIPLEXED ASSAY SIGNALS | ACLARA BIOSCIENCES, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| US-6258547-B1 | ENZYMATIC POLYPEPTIDE; FOR TREATMENT OF HYPERCHOLESTEROLAEMIA | ZENECA LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |
| EP-0698089-A1 | NUCLEIC ACID ENCODING AMP-ACTIVATED PROTEIN KINASE | ZENECA LIMITED (GB) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994028116-A1 | NUCLEIC ACID ENCODING AMP-ACTIVATED PROTEIN KINASE | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281084-B2 | Acetyl-CoA synthetase 2 (ACSS2) inhibitors and methods using same | ACSS2, ACACB, ACACA | ALDH1A1 170/4885PKM 1652/4885ACE 374/4885 |
| US-20220281826-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | ACSS2, ACACB, ACACA | ALDH1A1 170/4885PKM 1652/4885ACE 374/4885 |
| US-20250243168-A1 | ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME | ACSS2, ACACB, ACACA | ALDH1A1 170/4885PKM 1652/4885ACE 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.