Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479507 | 1.00 | ALDH1A1 (0.42) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL479503 | 1.00 | ALDH1A1 (0.42) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL2121338 | 0.91 | PDPK1 (0.41) | ALDH1A1KMT2ASIRT2CSF1RKDR | |
| SCHEMBL2121328 | 0.91 | PDPK1 (0.41) | ALDH1A1KMT2ASIRT2CSF1RKDR | |
| SCHEMBL479649 | 0.85 | RXFP1 (0.36) | MAPTRXFP1SIRT2CSF1RKDR | |
| SCHEMBL479654 | 0.85 | RXFP1 (0.36) | MAPTRXFP1SIRT2CSF1RKDR | |
| SCHEMBL3154576 | 0.83 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL3154570 | 0.83 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL480332 | 0.82 | RXFP1 (0.42) | ALDH1A1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL480330 | 0.82 | RXFP1 (0.42) | ALDH1A1RAB9AMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |