Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479654 | 1.00 | RXFP1 (0.36) | RXFP1CSF1RTP53THRBHDAC3 | |
| SCHEMBL479507 | 0.85 | ALDH1A1 (0.42) | RXFP1CSF1RTP53THRBKDR | |
| SCHEMBL479503 | 0.85 | ALDH1A1 (0.42) | RXFP1CSF1RTP53THRBKDR | |
| SCHEMBL479499 | 0.85 | ALDH1A1 (0.42) | RXFP1CSF1RTP53THRBKDR | |
| SCHEMBL479637 | 0.79 | RAB9A (0.38) | RXFP1CSF1RTP53THRBKDR | |
| SCHEMBL480332 | 0.78 | RXFP1 (0.42) | RXFP1TP53SIRT2SIRT1SIRT3 | |
| SCHEMBL480330 | 0.78 | RXFP1 (0.42) | RXFP1TP53SIRT2SIRT1SIRT3 | |
| SCHEMBL479493 | 0.78 | RAB9A (0.41) | CSF1RMAPTRET | |
| SCHEMBL3159910 | 0.78 | RXFP1 (0.42) | RXFP1TP53SIRT2SIRT1SIRT3 | |
| SCHEMBL3159898 | 0.78 | RXFP1 (0.42) | RXFP1TP53SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |