Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | CASP6 | P55212 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794432 | 0.79 | HTR2A (0.36) | CHEK1DAPK3GRK5LIMK1MEN1 | |
| SCHEMBL1064035 | 0.77 | MAPT (0.47) | MAPTCASP6MEN1POLBKMT2A | |
| SCHEMBL1064895 | 0.77 | MAPT (0.50) | MAPTCASP6MEN1POLBKMT2A | |
| SCHEMBL4782514 | 0.77 | FNTA (0.39) | CHEK1DAPK3GRK5LIMK1MAPT | |
| SCHEMBL1063743 | 0.75 | ALDH1A1 (0.47) | MAPTCASP6MEN1POLBKMT2A | |
| SCHEMBL1166073 | 0.75 | MAPT (0.54) | CHEK1DAPK3GRK5LIMK1MAPT | |
| SCHEMBL1064341 | 0.74 | MAPT (0.39) | MAPTCASP6MEN1POLBKMT2A | |
| SCHEMBL1064317 | 0.74 | MAPT (0.50) | MAPTCASP6MEN1POLBKMT2A | |
| SCHEMBL1063278 | 0.74 | CHRNB2 (0.51) | MAPTCASP6KDM4ELMNACYP19A1 | |
| SCHEMBL1063685 | 0.73 | CHRNB2 (0.39) | MAPTCASP6MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |