Formamide

Formamide

SCHEMBL4795044

Cc1noc(-c2ccccc2)c1C.NC=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.46
TDO2 P48775 1/20 0.46
BRD2 P25440 1/20 0.44
MAPT P10636 4/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LPAR1 Q92633 1/20 0.43
LPAR3 Q9UBY5 1/20 0.43
EDNRB P24530 5/20 0.42
EDNRA P25101 5/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
IP6K1 Q92551 1/20 0.40
PTPN1 P18031 1/20 0.40
TP53 P04637 2/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3751072 0.89 BRD4 (0.53) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL12000498 0.77 ALDH1A1 (0.46) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL3982046 0.77 ALDH1A1 (0.46) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL1754692 0.74 BRD4 (0.56) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL16021584 0.74 MAPT (0.47) MAPTKDM4EALDH1A1SMN1; SMN2EDNRB
SCHEMBL19287104 0.73 MAPT (0.51) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL1779686 0.73 BRD4 (0.42) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL21105338 0.72 BRD4 (0.68) BRD4TDO2BRD2MAPTKDM4E
SCHEMBL21105084 0.72 PTGS1 (0.55) BRD4BRD2MAPTALDH1A1SMN1; SMN2
SCHEMBL13388 0.71 BRD4 (0.53) BRD4TDO2BRD2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106986866-B Fungicidal azacyclic amides 杜邦公司 2020-03-03 CN disclosed
WO-2008013622-A2 FUNGICIDAL AZOCYCLIC AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-31 WO disclosed