Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | TDO2 | P48775 | 1/20 | 0.56 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13388 | 0.96 | BRD4 (0.53) | BRD4TDO2BRD2ALDH1A1MAPT | |
| SCHEMBL14789798 | 0.82 | RAB9A (0.40) | BRD4TDO2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13959385 | 0.82 | MAPK14 (0.40) | BRD4TDO2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13959849 | 0.82 | CHEK1 (0.48) | BRD4TDO2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13959362 | 0.81 | PTGS2 (0.42) | BRD4TDO2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1223 | 0.81 | MEN1 (0.39) | BRD4TDO2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3751072 | 0.79 | BRD4 (0.53) | BRD4TDO2BRD2ALDH1A1MAPT | |
| SCHEMBL13959846 | 0.79 | SMN1; SMN2 (0.44) | BRD4TDO2MAPTSMN1; SMN2KDM4E | |
| SCHEMBL13959867 | 0.78 | KMT2A (0.47) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL21105338 | 0.78 | BRD4 (0.68) | BRD4TDO2BRD2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. | 2011-12-08 | — | — | US | disclosed |
| CN-1056837-C | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 2000-09-27 | — | — | CN | disclosed |
| CN-1136810-A | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 1996-11-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | LPAR1, LPAR2, LPAR4 | BRD4 1510/4885TDO2 4512/4885BRD2 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.