Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291224 | 0.80 | POLB (0.42) | MCHR1ALDH1A1NPC1CYP3A4POLB | |
| SCHEMBL4980641 | 0.79 | MCHR1 (0.63) | MCHR1ALDH1A1NPC1CYP3A4POLB | |
| SCHEMBL14291533 | 0.75 | SIGMAR1 (0.41) | MCHR1ALDH1A1HPGDSIGMAR1KMT2A | |
| SCHEMBL4797658 | 0.75 | MCHR1 (0.62) | MCHR1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL4981461 | 0.72 | MCHR1 (0.52) | MCHR1ALDH1A1NPC1CYP3A4POLB | |
| SCHEMBL4843518 | 0.72 | MCHR1 (0.58) | MCHR1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL14290712 | 0.71 | POLB (0.50) | ALDH1A1POLBKMT2AGAA | |
| SCHEMBL4981131 | 0.71 | SSTR4 (0.59) | MCHR1ALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL14290836 | 0.71 | MCHR1 (0.54) | MCHR1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL14291049 | 0.70 | ACKR3 (0.47) | MCHR1CYP3A4KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |