Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 5/20 | 0.53 |
| ▸ | WNT3 | P56703 | 1/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | BRD2 | P25440 | 2/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4730801 | 0.99 | SFRP1 (0.52) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| SCHEMBL4616410 | 0.87 | SFRP1 (0.68) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4732691 | 0.86 | SFRP1 (0.67) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| SCHEMBL4623414 | 0.82 | BRD4 (0.55) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| SCHEMBL4847980 | 0.82 | SFRP1 (0.47) | SFRP1WNT3CCR8ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4785316 | 0.81 | SFRP1 (0.46) | SFRP1WNT3CCR8ALDH1A1L3MBTL1 | |
| SCHEMBL15917691 | 0.79 | MAPT (0.74) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| SCHEMBL4734388 | 0.78 | CCR8 (0.46) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| SCHEMBL5502165 | 0.78 | CCR8 (0.48) | SFRP1WNT3CCR8MAPTALDH1A1 | |
| SCHEMBL23045649 | 0.77 | KMT2A (0.61) | MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |