Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | WNT3 | P56703 | 1/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | BRD2 | P25440 | 2/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 8/20 | 0.41 |
| ▸ | HTR7 | P34969 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4734829 | 0.99 | CCR8 (0.46) | CCR8WNT3SFRP1DRD2HTR6 | |
| SCHEMBL15614423 | 0.90 | L3MBTL1 (0.51) | DRD2HTR6MAPTALDH1A1L3MBTL1 | |
| SCHEMBL4638693 | 0.83 | DRD2 (0.46) | CCR8DRD2HTR6MAPTALDH1A1 | |
| SCHEMBL6102370 | 0.81 | SFRP1 (0.66) | WNT3SFRP1 | |
| SCHEMBL4623414 | 0.81 | BRD4 (0.55) | CCR8WNT3SFRP1HTR6MAPT | |
| SCHEMBL4782205 | 0.79 | CA1 (0.50) | DRD2HTR6MAPTALDH1A1L3MBTL1 | |
| SCHEMBL4795211 | 0.78 | SFRP1 (0.53) | CCR8WNT3SFRP1MAPTALDH1A1 | |
| SCHEMBL15917691 | 0.78 | MAPT (0.74) | CCR8WNT3SFRP1MAPTALDH1A1 | |
| SCHEMBL4733468 | 0.78 | DRD2 (0.49) | CCR8WNT3SFRP1DRD2HTR6 | |
| Hydrochloric Acid SCHEMBL4730801 | 0.77 | SFRP1 (0.52) | CCR8WNT3SFRP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |