Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 5/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581959 | 0.77 | ELANE (0.37) | USP14CYP19A1CTSSCTSK | |
| SCHEMBL4579431 | 0.76 | NR3C2 (0.36) | USP14CYP19A1NR3C2CTSSCTSK | |
| SCHEMBL4580904 | 0.76 | CYP19A1 (0.36) | USP14CYP19A1PRMT5WDR77NR3C2 | |
| SCHEMBL19745831 | 0.62 | CNR2 (0.46) | USP14CNR2NR3C2NPC1RAB9A | |
| SCHEMBL19745832 | 0.62 | CNR2 (0.46) | USP14CNR2NR3C2NPC1RAB9A | |
| SCHEMBL4580525 | 0.62 | CCR1 (0.38) | NPC1RAB9A | |
| SCHEMBL16480373 | 0.62 | POLB (0.46) | CNR2 | |
| SCHEMBL4581779 | 0.61 | AR (0.38) | AR | |
| SCHEMBL16790795 | 0.61 | MAOA (0.44) | CYP19A1NPC1RAB9A | |
| SCHEMBL4579589 | 0.61 | PARP10 (0.35) | CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024970-A2 | TETRAHYDROINDOLONE AND TETRAHYDROINDAZOLONE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | claimed |