SCHEMBL16790795

SCHEMBL16790795

N#Cc1ccc(N2C(=C3N(c4ccc(C#N)cc4)C4CCCCC4N3c3ccc(C#N)cc3)N(c3ccc(C#N)cc3)C3CCCCC32)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
HRH3 Q9Y5N1 14/20 0.43
KCNH2 Q12809 1/20 0.43
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
HTR7 P34969 1/20 0.39
CYP19A1 P11511 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16790773 0.79 DRD2 (0.49) HRH3
SCHEMBL16789231 0.74 MAPT (0.40) HRH3
SCHEMBL16789226 0.73 SLC18A3 (0.43) TP53NPC1RAB9A
SCHEMBL17954587 0.71 GRM5 (0.39) MAOAMAOBHRH3KCNH2
SCHEMBL16789229 0.71 HRH3 (0.45) HRH3NPC1RAB9A
SCHEMBL24295264 0.69 USP14 (0.45) MAOAMAOBHRH3KDM4ETP53
SCHEMBL5017575 0.69 USP14 (0.45) MAOAMAOBHRH3KDM4ETP53
SCHEMBL16789244 0.69 L3MBTL1 (0.46) TP53NPC1RAB9A
SCHEMBL16789228 0.69 NPY1R (0.40) RAB9A
SCHEMBL11543438 0.69 ALDH1A1 (0.50) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-9846385-B2 Organic light emitting element and display device CANON KABUSHIKI KAISHA (JP) 2017-12-19 US disclosed
US-20150162549-A1 ORGANIC LIGHT EMITTING ELEMENT AND DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2015-06-11 US disclosed