Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 12/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479556 | 1.00 | SIGMAR1 (0.42) | SIGMAR1TMEM97RXFP1LTA4HMAPT | |
| SCHEMBL479558 | 1.00 | SIGMAR1 (0.42) | SIGMAR1TMEM97RXFP1LTA4HMAPT | |
| SCHEMBL480368 | 0.95 | RXFP1 (0.41) | SIGMAR1TMEM97RXFP1MAPTNAMPT | |
| SCHEMBL480369 | 0.95 | RXFP1 (0.41) | SIGMAR1TMEM97RXFP1MAPTNAMPT | |
| SCHEMBL3153480 | 0.93 | SIGMAR1 (0.42) | SIGMAR1TMEM97LTA4HOPRM1ACKR3 | |
| SCHEMBL3153463 | 0.93 | SIGMAR1 (0.42) | SIGMAR1TMEM97LTA4HOPRM1ACKR3 | |
| SCHEMBL479382 | 0.91 | RXFP1 (0.42) | SIGMAR1TMEM97RXFP1LTA4HMAPT | |
| SCHEMBL479383 | 0.91 | RXFP1 (0.42) | SIGMAR1TMEM97RXFP1LTA4HMAPT | |
| SCHEMBL2566845 | 0.91 | RXFP1 (0.42) | SIGMAR1TMEM97RXFP1LTA4HMAPT | |
| SCHEMBL480611 | 0.91 | RXFP1 (0.44) | RXFP1LTA4HMAPTNAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |