Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4795693

C[N+](C)(C)Cc1ccc(C[N+](C)(C)C)cc1.[Cl-].[Cl-]

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.39
CHRM1 known ✓ P11229 2/20 0.39
CHRM3 known ✓ P20309 1/20 0.39
ALDH1A1 P00352 2/20 0.74
KDM4E B2RXH2 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
CHRNB2 P17787 1/20 0.52
CHRNA4 P43681 1/20 0.52
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CYP2C9 P11712 1/20 0.39
PSMD14 O00487 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MMP2 P08253 1/20 0.38
MC4R P32245 1/20 0.38
RAD52 P43351 1/20 0.38
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4797252 0.97 ALDH1A1 (0.68) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL6772823 0.89 TDP1 (0.61) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL28552029 0.89 ALDH1A1 (0.61) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
SCHEMBL13432944 0.88 ALDH1A1 (0.59) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL22264942 0.87 KDM4E (0.58) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL28238682 0.87 ALDH1A1 (0.58) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL10570286 0.87 ALDH1A1 (0.58) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL10453138 0.87 TDP1 (0.58) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL8616233 0.87 ALDH1A1 (0.58) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL932070 0.87 KDM4E (0.58) ALDH1A1KDM4ETDP1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7344780-B2 Can form coating directly on a metal surface without using any primer, and improve the resistance to antifreezes and the degradation of a coating film when it is compressed at a high temperature for a long time DAIKIN INDUSTRIES, LTD. (JP) 2008-03-18 US disclosed
EP-1167442-B1 WATER-BASED VULCANIZABLE FLUORORUBBER COMPOSITION AND ARTICLE COATED WITH FLUORORUBBER DAIKIN IND LTD (JP) 2005-07-13 EP disclosed
US-20050085576-A1 Mixture containing curing agent and quaternary ammonium compound DAIKIN INDUSTRIES, LTD. (JP) 2005-04-21 US disclosed
EP-1486544-A1 FLUORORUBBER COATING COMPOSITION Daikin Industries, Ltd. (JP) 2004-12-15 EP disclosed
US-20040214944-A1 Aqueous fluoroelastomer curable composition and coated article DAIKIN INDUSTRIES, LTD. 2004-10-28 US disclosed
US-6764763-B1 Water-based vulcanizable fluororubber composition and coated article DAIKIN INDUSTRIES LTD. (JP) 2004-07-20 US disclosed
US-6720381-B1 DURABLE COATING FOR PRINTER ROLL; NONIONIC POLYOXYETHYLENE GLYCOL SURFACTANT IS NOT ENDCAPPED WITH A PHENYL GROUP DAIKIN INDUSTRIES, LTD. (JP) 2004-04-13 US disclosed
US-6664336-B1 Composition comprising fluoroelastomer, fluororesin, curing agent and surfactant, wherein surfactant leaves 0.3 wt. % or less of decomposition residue after being heated at 300 degrees C. for 30 minutes DAIKIN INDUSTRIES, LTD. (JP) 2003-12-16 US disclosed
US-20030157336-A1 Fluororubber coating composition DAIKIN INDUSTRIES, LTD. (JP) 2003-08-21 US disclosed
EP-0921155-B1 FLUORORUBBER COATING COMPOSITION DAIKIN IND LTD (JP) 2003-05-02 EP disclosed
EP-1291401-A1 FLUORORUBBER COATING COMPOSITION Daikin Industries, Ltd. (JP) 2003-03-12 EP disclosed
EP-1245634-A1 WATER-BASED COMPOSITION FOR FLUORORUBBER VULCANIZATION AND ARTICLE COATED WITH FLUORORUBBER Daikin Industries, Ltd. (JP) 2002-10-02 EP disclosed
EP-0769517-B1 SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT DAIKIN IND LTD (JP) 2002-09-18 EP disclosed
EP-1170120-A1 ARTICLE COATED WITH FLUORORESIN AND METHOD FOR PRODUCING THE SAME Daikin Industries, Ltd. (JP) 2002-01-09 EP disclosed
EP-1167442-A1 WATER-BASED VULCANIZABLE FLUORORUBBER COMPOSITION AND ARTICLE COATED WITH FLUORORUBBER Daikin Industries, Ltd. (JP) 2002-01-02 EP disclosed
EP-1138718-A1 AQUEOUS COMPOSITION FOR VULCANIZATION OF FLUORO RUBBER AND ARTICLE COATED WITH FLUORO RUBBER Daikin Industries, Ltd. (JP) 2001-10-04 EP disclosed
EP-1065243-A1 WATER-BASED VULCANIZABLE FLUORORUBBER COMPOSITION AND COATED ARTICLE Daikin Industries, Ltd. (JP) 2001-01-03 EP disclosed
EP-0921155-A1 FLUORORUBBER COATING COMPOSITION DAIKIN INDUSTRIES, LIMITED (JP) 1999-06-09 EP disclosed
US-5684065-A LASER BEAM DAIKIN INDUSTRIES, LTD. (JP) 1997-11-04 US disclosed
EP-0769517-A1 SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 1997-04-23 EP disclosed