Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.69 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.69 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274068 | 0.77 | NPSR1 (1.00) | GAASMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL4797401 | 0.71 | ALDH1A1 (1.00) | GAASMN1; SMN2L3MBTL1LMNAMAPT | |
| SCHEMBL19269468 | 0.71 | MAPT (0.60) | GAASMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL6403299 | 0.70 | KMT2A (0.63) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL16157170 | 0.69 | TP53 (0.81) | GAASMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL6405002 | 0.69 | ALDH1A1 (0.64) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL6408123 | 0.69 | ALDH1A1 (0.63) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL17068793 | 0.69 | MAPT (0.74) | GAASMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL26227653 | 0.69 | MAPT (0.67) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL16157172 | 0.68 | MAPT (0.80) | SMN1; SMN2L3MBTL1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | disclosed |