Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GALK1 | P51570 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408123 | 0.79 | ALDH1A1 (0.63) | KMT2AHTTALDH1A1MAPTUSP2 | |
| SCHEMBL6405002 | 0.74 | ALDH1A1 (0.64) | KMT2AHTTALDH1A1MAPTUSP2 | |
| SCHEMBL12310045 | 0.73 | ALDH1A1 (0.67) | KMT2AHTTALDH1A1MAPTUSP2 | |
| SCHEMBL4795877 | 0.70 | GAA (0.79) | KMT2AHTTALDH1A1MAPTLMNA | |
| SCHEMBL6890807 | 0.68 | KMT2A (0.49) | KMT2AALDH1A1NPSR1CYP1A2CYP2C19 | |
| SCHEMBL4556566 | 0.67 | MAPK1 (0.68) | KMT2AMAPTMEN1NPSR1POLB | |
| SCHEMBL4759685 | 0.67 | BCHE (0.65) | KMT2AALDH1A1MAPTUSP2MEN1 | |
| SCHEMBL4759501 | 0.67 | BCHE (0.65) | KMT2AALDH1A1MAPTUSP2MEN1 | |
| SCHEMBL627575 | 0.67 | BCHE (0.65) | ALDH1A1MAPTUSP2NPSR1POLB | |
| SCHEMBL2681239 | 0.67 | BCHE (0.70) | KMT2AALDH1A1MAPTUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | KMT2A 2263/4885HTT 2113/4885ALDH1A1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.