Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669383 | 0.93 | CYP3A4 (0.37) | POLBMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3665336 | 0.89 | CHRM5 (0.36) | TSHR | |
| SCHEMBL3665332 | 0.86 | POLB (0.35) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4796847 | 0.85 | POLB (0.41) | POLBMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4796839 | 0.85 | POLB (0.41) | POLBMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3665443 | 0.85 | RXFP1 (0.36) | ALDH1A1 | |
| SCHEMBL3808537 | 0.81 | CACNA1G (0.34) | CYP3A4PKM | |
| SCHEMBL4675598 | 0.81 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL3668869 | 0.81 | BCHE (0.33) | POLBALDH1A1 | |
| SCHEMBL3667342 | 0.80 | CHRM1 (0.34) | MAPTCYP3A4CYP2C19TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |