Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315214 | 0.89 | KDM4E (0.66) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL3308582 | 0.85 | KMT2A (0.83) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL3314479 | 0.83 | MEN1 (0.81) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL3312796 | 0.79 | PKM (0.67) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL23052562 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL23052499 | 0.77 | MEN1 (0.74) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL23052455 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL23052564 | 0.77 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL23052359 | 0.77 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL23052324 | 0.76 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045663-A2 | ARYL-SUBSTITUTED HETEROCYCLIC PDE4 INHIBITORS AS ANTIINFLAMMATORY AGENTS | KALYPSYS, INC. (US) | 2008-04-17 | — | — | WO | disclosed |