SCHEMBL4797237

SCHEMBL4797237

COC(OC)=C(OC)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
SRC P12931 1/20 0.41
HPGD P15428 3/20 0.39
CES1 P23141 3/20 0.39
CES2 O00748 1/20 0.39
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.38
NPC1 O15118 6/20 0.37
RAB9A P51151 5/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HTT P42858 2/20 0.37
ALDH1A1 P00352 1/20 0.37
SLC6A3 Q01959 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10873087 0.87 TSHR (0.56) TSHRSRCHPGDCES1CES2
SCHEMBL4019330 0.87 TSHR (0.56) TSHRSRCHPGDCES1CES2
SCHEMBL1603720 0.87 TSHR (0.56) TSHRSRCHPGDCES1CES2
SCHEMBL9311224 0.82 TSHR (0.52) TSHRSRCHPGDCES1CES2
SCHEMBL4629606 0.78 TSHR (0.48) TSHRSRCHPGDCES1CES2
SCHEMBL2996805 0.78 TSHR (0.54) TSHRSRCHPGDCES1CES2
SCHEMBL25137340 0.77 TSHR (0.52) TSHRSRCHPGDCES1CES2
SCHEMBL27691329 0.77 TSHR (0.52) TSHRSRCHPGDCES1CES2
SCHEMBL7039288 0.76 TSHR (0.46) TSHRSRCHPGDCES1CES2
SCHEMBL3309374 0.76 TSHR (0.46) TSHRSRCHPGDCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP claimed
US-20080177022-A1 HYDROPHILIC FILM FORMING COMPOSITION AND HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
EP-1923363-A2 Hydrophilic member and substrate for hydrophilic member FUJIFILM Corporation (JP) 2008-05-21 EP disclosed
US-20080102286-A1 HYDROPHILIC MEMBER AND SUBSTRATE FOR HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2008-05-01 US disclosed
US-7049264-B1 An olefin polymerization catalyst containing as a support, a styrenic copolymer, a metallocene complex and a compound capable of forming metallocinium ions BASELL POLYOLEFINE GMBH (DE) 2006-05-23 US disclosed
EP-1165486-B1 IONIC LIQUIDS UNIV LEICESTER (GB) 2005-06-22 EP disclosed
EP-1189950-B1 SUPPORT CATALYST FOR OLEFIN POLYMERIZATION BASELL POLYOLEFINE GMBH (DE) 2004-05-12 EP disclosed
US-6573405-B1 Liquid having a melting point of no more than 60 degrees C., formed by the reaction of a quaternary ammonium compound of the formula: R1R2R3R4N+X- (I) or a mixture of two or more therof; with a halide of zinc, tin or iron, or a mixture of SCIONIX LIMITED (GB) 2003-06-03 US disclosed
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP disclosed
US-6388020-B2 MODIFIED WITH LESS THAN 5% BY WEIGHT OF MONOFUNCTIONAL, DIFUNCTIONAL AND POLYFUNCTIONAL MONOMERS; IMPROVED MELT PROCESSABILITY; SHEETS, FILMS, PANELS, COATINGS, PIPES, HOLLOW OBJECTS AND FOAMS BOREALIS GMBH (AT) 2002-05-14 US disclosed
EP-1165486-A1 IONIC LIQUIDS UNIVERSITY OF LEICESTER (GB) 2002-01-02 EP disclosed
US-20010016628-A1 Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams BOREALIS GMBH (AU) 2001-08-23 US disclosed
WO-2000078823-A1 SUPPORT CATALYST FOR OLEFIN POLYMERIZATION BASELL POLYOLEFINE GMBH (DE) 2000-12-28 WO disclosed
WO-2000056700-A1 IONIC LIQUIDS UNIVERSITY OF LEICESTER (GB) 2000-09-28 WO disclosed
EP-0792894-A2 Continuous modification of polyolefins in solid phase PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed
US-5326489-A Sulfonated polymer NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
US-5314978-A Copolymer of sulfur dioxide and nuclear-substituted trialkylgermylstyrene KUMHO PETROCHEMICAL COMPANY, LIMITED (KR) 1994-05-24 US disclosed
EP-0523300-B1 Electrorheological fluids NIPPON CATALYTIC CHEM IND (JP) 1994-01-19 EP disclosed
EP-0523300-A1 Electrorheological fluids NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1993-01-20 EP disclosed