Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873087 | 0.88 | TSHR (0.56) | TSHRALDH1A1TDP1HSD17B10F2 | |
| SCHEMBL4019330 | 0.88 | TSHR (0.56) | TSHRALDH1A1TDP1HSD17B10F2 | |
| SCHEMBL1603720 | 0.88 | TSHR (0.56) | TSHRALDH1A1TDP1HSD17B10F2 | |
| SCHEMBL9311224 | 0.78 | TSHR (0.52) | TSHRALDH1A1TDP1F2LMNA | |
| SCHEMBL3309374 | 0.77 | TSHR (0.46) | TSHRALDH1A1TDP1HSD17B10F2 | |
| SCHEMBL16213551 | 0.77 | CES2 (0.52) | TSHRTDP1LMNACES2KMT2A | |
| SCHEMBL4797237 | 0.76 | TSHR (0.50) | TSHRALDH1A1TDP1F2LMNA | |
| SCHEMBL7763555 | 0.76 | TSHR (0.45) | TSHRALDH1A1TDP1HSD17B10LMNA | |
| SCHEMBL4629606 | 0.74 | TSHR (0.48) | TSHRALDH1A1LMNASRCHPGD | |
| SCHEMBL1055303 | 0.73 | TSHR (0.46) | TSHRALDH1A1TDP1F2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004083943-A2 | LIQUID CRYSTAL DISPLAY DEVICE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2004-09-30 | — | — | WO | disclosed |