Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.39 |
| ▸ | CDK1 | P06493 | 6/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.37 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797785 | 0.82 | HDAC6 (0.47) | ADORA2AADORA1 | |
| SCHEMBL4796358 | 0.81 | ADORA2A (0.39) | ADORA2AADORA1CDK1CCNB1CCNE1 | |
| SCHEMBL4798283 | 0.81 | ADORA2A (0.39) | ADORA2AADORA1CDK1CCNB1CCNE1 | |
| SCHEMBL4796781 | 0.74 | ADORA2A (0.32) | ADORA2AADORA1PARP1 | |
| SCHEMBL3272905 | 0.70 | HDAC6 (0.48) | ADORA2AADORA1 | |
| SCHEMBL4446276 | 0.70 | XDH (0.54) | — | |
| SCHEMBL27854858 | 0.69 | CDK1 (0.53) | ADORA2AADORA1CDK1CCNB1CCNE1 | |
| SCHEMBL2346678 | 0.68 | GSK3B (0.67) | ADORA2AADORA1ADORA2BGSK3B | |
| SCHEMBL4799051 | 0.68 | HSP90AB1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL29003046 | 0.67 | GSK3B (0.65) | ADORA2AADORA1ADORA2BGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321035-B2 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-01-22 | — | — | US | disclosed |
| US-6936713-B2 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-30 | — | — | US | disclosed |
| US-20050090666-A1 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1375502-A1 | PROCESS FOR PRODUCING 2,6-DIHALOGENOPURINE | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-20030144508-A1 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |