Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782600 | 0.91 | GRM1 (0.51) | GRM1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4798176 | 0.87 | GRM1 (0.55) | GRM1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL4780726 | 0.87 | MAPT (0.53) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4802240 | 0.85 | RAB9A (0.47) | GRM1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL3341175 | 0.84 | GRM1 (0.59) | GRM1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL4797120 | 0.84 | GRM1 (0.59) | GRM1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL4799024 | 0.82 | KMT2A (0.53) | GRM1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL4800674 | 0.81 | GRM1 (0.57) | GRM1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL4845367 | 0.81 | RAB9A (0.45) | GRM1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4780298 | 0.79 | MIF (0.53) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | claimed |