Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495806 | 0.90 | KIF11 (0.50) | KIF11GRM2GRM3SLC1A1SLC1A3 | |
| SCHEMBL4990298 | 0.82 | KIF11 (0.57) | KIF11GRM2GRM3SLC1A1SLC1A3 | |
| SCHEMBL14975565 | 0.76 | KIF11 (0.43) | KIF11GRM2GRM3SLC1A1SLC1A3 | |
| SCHEMBL3785507 | 0.76 | FOLH1 (0.48) | KIF11 | |
| SCHEMBL34784 | 0.76 | FOLH1 (0.48) | KIF11 | |
| SCHEMBL29351710 | 0.72 | KIF11 (0.48) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL29053899 | 0.72 | KIF11 (0.68) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL29053902 | 0.72 | KIF11 (0.68) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL27346918 | 0.71 | TSHR (0.47) | KIF11GRIK1 | |
| SCHEMBL27349964 | 0.71 | TSHR (0.47) | KIF11GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089256-A2 | POLYMERIC THERAPEUTICS | CAPPELLA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |