Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11280337 | 1.00 | — | — | |
| Bicarbonate SCHEMBL29181726 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL28577539 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL27082179 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL28358443 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL12489460 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL641446 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL2890152 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL5082549 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3LCK | |
| Bicarbonate SCHEMBL27691058 | 0.94 | CA1 (0.62) | CA1CA2CA9FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688908-A2 | CROSSLINKED POLYESTER ELASTOMERS, COMPOSITIONS, AND METHODS OF PREPARATION THEREOF | Momentive Performance Materials Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| EP-3768816-B1 | METHOD AND DEVICE FOR THE PRESERVATION OF LIQUIDS CONTAINING WINE | LANXESS DEUTSCHLAND GMBH (DE) | 2025-10-08 | — | — | EP | claimed |
| US-20250215003-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB | GRANULES INDIA LIMITED (IN) | 2025-07-03 | — | — | US | claimed |
| US-12288877-B2 | Rechargeable metal halide battery with intercalation anode | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2025-04-29 | — | — | US | claimed |
| WO-2025071268-A1 | POLYESTER RESIN HAVING EXCELLENT MECHANICAL PROPERTIES AND BIODEGRADABILITY, AND PREPARATION METHOD THEREFOR | 주식회사 삼양사 | 2025-04-03 | — | — | WO | claimed |
| EP-3713848-B1 | DICARBONIC ACID CONTAINING ALUMINIUM CONTAINER | LANXESS DEUTSCHLAND GMBH (DE) | 2025-03-12 | — | — | EP | claimed |
| US-12234234-B2 | Method for synthesizing 1,7-naphthyridine derivatives | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2025-02-25 | — | — | US | claimed |
| CN-116375706-B | Abamectin sodium key intermediate and preparation method thereof | 时森海(杭州)医药科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119032095-A | Improved process for preparing ruxolitinib | 印度颗粒有限公司 | 2024-11-26 | — | — | CN | claimed |
| EP-4463460-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB | Granules India Limited (IN) | 2024-11-20 | — | — | EP | claimed |
| EP-1174940-A1 | Non-aqueous electrochemical apparatus | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | claimed |
| US-20010038949-A1 | Stability; electrolyte mixture containing surfactant | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2001-11-08 | — | — | US | claimed |
| EP-1146586-A2 | Non-aqueous electrolyte secondary battery | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2001-10-17 | — | — | EP | claimed |
| US-20010008658-A1 | ADDITIVE TRANSFER FILM SUITABLE FOR COOK-IN END USE | CRYOVAC, INC. | 2001-07-19 | — | — | US | claimed |
| US-6153696-A | Process for forming carbonates of hydroxyaromatic compounds | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2000-11-28 | — | — | US | claimed |
| US-6020386-A | REACTING A POLY(UREA)URETHANE WITH WASTES WITH POLYOL; HEATING; THEN DIALKYL CARBONATE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | claimed |
| EP-0954545-A1 | ADDITIVE TRANSFER FILM SUITABLE FOR COOK-IN END USE | Cryovac, Inc. (US) | 1999-11-10 | — | — | EP | claimed |
| EP-0610719-B1 | Process for the preparation of hydroxyl group containing compounds from (polyurethane) polyurea waste | BAYER AG (DE) | 1999-04-07 | — | — | EP | claimed |
| WO-1998031731-A1 | ADDITIVE TRANSFER FILM SUITABLE FOR COOK-IN END USE | CRYOVAC, INC. (US) | 1998-07-23 | — | — | WO | claimed |
| US-4087543-A | Composition for disinfecting soil and combating plant diseases containing organic dicarbonates | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12234234-B2 | Method for synthesizing 1,7-naphthyridine derivatives | ALDH7A1, AKR7A2, APEH | CA1 1106/4885CA2 1013/4885CA9 231/4885 |
| US-20250215003-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB | JAK1, JAK3, JAK2 | CA1 4690/4885CA2 4017/4885CA9 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.