Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479830 | 1.00 | TP53 (0.52) | TP53TSHREPHX1EPHX2CDK9 | |
| SCHEMBL3078893 | 0.88 | TP53 (0.52) | TP53TSHREPHX1EPHX2CDK9 | |
| SCHEMBL3078896 | 0.88 | TP53 (0.52) | TP53TSHREPHX1EPHX2CDK9 | |
| SCHEMBL4318168 | 0.81 | NPC1 (0.59) | SMN1; SMN2MAPTGAATGM2HSD17B10 | |
| SCHEMBL4318165 | 0.81 | NPC1 (0.59) | SMN1; SMN2MAPTGAATGM2HSD17B10 | |
| SCHEMBL3077709 | 0.79 | ALDH1A1 (0.59) | TP53TSHREPHX1MAPTGAA | |
| SCHEMBL3077704 | 0.79 | ALDH1A1 (0.59) | TP53TSHREPHX1MAPTGAA | |
| SCHEMBL14482453 | 0.78 | EPHX1 (0.50) | TP53TSHREPHX1EPHX2CDK9 | |
| SCHEMBL11772923 | 0.78 | MAPT (0.56) | TP53TSHREPHX1EPHX2CDK9 | |
| SCHEMBL11772931 | 0.78 | MAPT (0.56) | TP53TSHREPHX1EPHX2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411367-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010109123-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-30 | — | — | WO | disclosed |