Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.56 |
| ▸ | HTR3B | O95264 | 2/20 | 0.56 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318168 | 1.00 | NPC1 (0.59) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL479830 | 0.81 | TP53 (0.52) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL479832 | 0.81 | TP53 (0.52) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8623933 | 0.81 | MEN1 (0.59) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL29217646 | 0.81 | MAPT (0.59) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8623927 | 0.81 | MEN1 (0.59) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL167193 | 0.79 | MEN1 (0.71) | NPC1RAB9AMAPTMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28790660 | 0.78 | MEN1 (0.69) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL1884170 | 0.77 | MEN1 (0.74) | NPC1RAB9AMAPTMEN1KMT2A | |
| Bicarbonate SCHEMBL15057748 | 0.77 | MEN1 (0.62) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |