Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722960 | 1.00 | FFAR2 (0.54) | FFAR2ACEPREPMEN1USP2 | |
| SCHEMBL4800296 | 0.85 | FFAR2 (0.52) | FFAR2PREPMEN1KMT2A | |
| SCHEMBL4798814 | 0.83 | FFAR2 (0.47) | FFAR2ACEPREPMEN1USP2 | |
| SCHEMBL4800187 | 0.82 | ACE (0.48) | FFAR2ACEPREPMEN1USP2 | |
| SCHEMBL4800001 | 0.82 | FFAR2 (0.47) | FFAR2ACEPREPMEN1USP2 | |
| SCHEMBL4798679 | 0.80 | FFAR2 (0.45) | FFAR2ACEPREPMEN1USP2 | |
| SCHEMBL4800042 | 0.79 | FFAR2 (0.44) | FFAR2ACEPREPMEN1USP2 | |
| SCHEMBL3208860 | 0.79 | FFAR2 (0.52) | FFAR2 | |
| SCHEMBL9713852 | 0.78 | DPP4 (0.55) | PREP | |
| SCHEMBL9370167 | 0.78 | FFAR2 (0.43) | FFAR2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439036-B2 | Process for producing optically active octahydro-1H-indole-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-21 | — | — | US | disclosed |
| EP-1536017-B1 | Process for producing optically active octahydro-1H-indole-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1536017-A2 | Process for producing optically active octahydro-1H-indole-2-carboxylic acid | Sumitomo Chemical Company, Limited (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-20050106690-A1 | Process for producing optically active octahydro-1H-indole-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-05-19 | — | — | US | disclosed |
| EP-0088341-B1 | SUBSTITUTED ACYL DERIVATIVE OF OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1987-07-22 | — | — | EP | disclosed |
| EP-0037231-B1 | SUBSTITUTED ACYL DERIVATIVES OF OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 1987-01-28 | — | — | EP | disclosed |
| US-4425355-A | HYPOTENSIVE | WARNER-LAMBERT COMPANY (US) | 1984-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050106690-A1 | Process for producing optically active octahydro-1H-indole-2-carboxylic acid | IDO1, IDO2, APEH | FFAR2 355/4885ACE 1148/4885PREP 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.