Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.48 |
| ▸ | FAP | Q12884 | 3/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12787635 | 1.00 | DPP4 (0.55) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL6870444 | 1.00 | DPP4 (0.55) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10722960 | 0.78 | FFAR2 (0.54) | PREP | |
| SCHEMBL4799439 | 0.78 | FFAR2 (0.54) | PREP | |
| SCHEMBL10794375 | 0.76 | DPP4 (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8291743 | 0.76 | DPP4 (0.46) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL9370167 | 0.75 | FFAR2 (0.43) | PREP | |
| SCHEMBL9732210 | 0.75 | DPP4 (0.45) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL9732206 | 0.75 | DPP4 (0.45) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10793158 | 0.73 | DPP4 (0.49) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267098-B1 | PROCESS FOR THE PREPARATION OF OCTAHYDROINDOLE DERIVATIVES AND THEIR INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1992-01-22 | — | — | EP | disclosed |
| EP-0267098-A1 | Process for the preparation of octahydroindole derivatives and their intermediates | ROUSSEL-UCLAF (FR) | 1988-05-11 | — | — | EP | disclosed |