Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PLD2 | O14939 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670916 | 0.83 | CHRM2 (0.38) | BCHEACHECALCRLHSD11B1PLD1 | |
| SCHEMBL1832858 | 0.80 | OPRM1 (0.52) | CALCRLHSD11B1PLD1OPRM1KDM4E | |
| SCHEMBL1832853 | 0.80 | OPRM1 (0.52) | CALCRLHSD11B1PLD1OPRM1KDM4E | |
| SCHEMBL4677517 | 0.78 | OPRM1 (0.49) | HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL1837752 | 0.78 | TNKS (0.51) | BCHEACHECALCRLHSD11B1OPRM1 | |
| SCHEMBL1835272 | 0.78 | OPRM1 (0.50) | BCHEACHEPLD1OPRM1KDM4E | |
| SCHEMBL3403017 | 0.78 | OPRM1 (0.50) | BCHEACHEPLD1OPRM1KDM4E | |
| SCHEMBL3810390 | 0.77 | CALCRL (0.35) | BCHEACHECALCRLHSD11B1PLD1 | |
| SCHEMBL1836672 | 0.76 | OPRM1 (0.44) | BCHEACHECALCRLHSD11B1OPRM1 | |
| SCHEMBL4803178 | 0.75 | KDM4E (0.43) | BCHEACHECALCRLHSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |