Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677524 | 0.81 | OPRM1 (0.49) | OPRM1OPRL1OPRK1HSD11B1CHRNB4 | |
| SCHEMBL4677520 | 0.81 | OPRM1 (0.49) | OPRM1OPRL1OPRK1HSD11B1CHRNB4 | |
| SCHEMBL4681484 | 0.81 | AGTR2 (0.48) | — | |
| SCHEMBL4799701 | 0.78 | BCHE (0.36) | OPRM1OPRL1OPRK1HSD11B1 | |
| SCHEMBL4675598 | 0.76 | CYP3A4 (0.40) | OPRM1OPRL1TNKSPARP1PARP2 | |
| SCHEMBL4676164 | 0.75 | HSD11B1 (0.44) | TNKSPARP1PARP2HSD11B1 | |
| SCHEMBL3403017 | 0.75 | OPRM1 (0.50) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4677514 | 0.75 | OPRM1 (0.48) | OPRM1OPRL1OPRK1CHRNB4CHRNA3 | |
| SCHEMBL1835272 | 0.75 | OPRM1 (0.50) | OPRM1OPRL1OPRK1 | |
| SCHEMBL1838649 | 0.74 | DRD2 (0.41) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |