Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.65 |
| ▸ | CTSL | P07711 | 14/20 | 0.65 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799709 | 1.00 | CTSS (0.65) | CTSSCTSLCTSK | |
| SCHEMBL4799039 | 0.83 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL4799030 | 0.83 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL4799033 | 0.83 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL6691378 | 0.76 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL4798600 | 0.76 | CTSS (0.90) | CTSSCTSLCTSK | |
| SCHEMBL4798591 | 0.76 | CTSS (0.90) | CTSSCTSLCTSK | |
| SCHEMBL4799505 | 0.73 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL4799511 | 0.73 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL4799131 | 0.71 | CTSS (1.00) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384970-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2008-06-10 | — | — | US | disclosed |