Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.60 |
| ▸ | CTSL | P07711 | 15/20 | 0.60 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690823 | 0.87 | CTSS (0.66) | CTSSCTSLCTSK | |
| SCHEMBL6693567 | 0.86 | CTSS (0.68) | CTSSCTSLCTSK | |
| SCHEMBL6691061 | 0.83 | CTSS (0.56) | CTSSCTSLCTSK | |
| SCHEMBL4799033 | 0.81 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL4799039 | 0.81 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL4799030 | 0.81 | CTSS (0.89) | CTSSCTSLCTSK | |
| SCHEMBL6689440 | 0.81 | CTSS (0.57) | CTSSCTSLCTSK | |
| SCHEMBL6693488 | 0.81 | CTSS (0.61) | CTSSCTSLCTSK | |
| SCHEMBL4799729 | 0.76 | CTSS (0.65) | CTSSCTSLCTSK | |
| SCHEMBL4799709 | 0.76 | CTSS (0.65) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |