Toluene

Toluene

SCHEMBL48006

C1CCCCC1.Cc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.79
TSHR P16473 2/20 0.79
LMNA P02545 2/20 0.79
ALOX12 P18054 1/20 0.79
TDP1 Q9NUW8 2/20 0.47
HPGD P15428 2/20 0.46
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
POLB P06746 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
HTT P42858 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP2C19 P33261 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL1289937 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL1289945 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL11529127 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL598534 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
Cyclooctane SCHEMBL16909938 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL23491537 1.00 ACHE (0.79) ACHETSHRLMNAALOX12TDP1
P-Xylene SCHEMBL9750677 0.97 ACHE (0.73) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL4429042 0.89 ACHE (1.00) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL175861 0.89 ACHE (1.00) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL4535818 0.89 ACHE (1.00) ACHETSHRLMNAALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109304098-B Preparation method of polymer-ceramic composite inner membrane 南京工业大学 2022-02-25 CN claimed
CN-212942292-U Graphite retort pitch tail gas processing apparatus 广东凯金新能源科技股份有限公司 2021-04-13 CN claimed
CN-106544100-A A kind of lubricating oil 苏州宇希新材料科技有限公司 2017-03-29 CN claimed
CN-104897597-A Detection reagent of nucleic acid preparation and detection method for nucleic acid preparation XIAMEN CHENGKUN BIOTECHNOLOGY CO LTD 2015-09-09 CN claimed
WO-2011022086-A1 A METHOD OF STORING AND TRANSPORTING LIGHT GASES SYNFUELS INTERNATIONAL, INC. (US) 2011-02-24 WO claimed
US-20110041518-A1 METHOD OF STORING AND TRANSPORTING LIGHT GASES SYNFUELS INTERNATIONAL, INC. (US) 2011-02-24 US claimed
US-7282517-B2 Method of manufacturing glimepiride and the respective intermediate ZENTIVA, A.S. (CZ) 2007-10-16 US claimed
US-20070054954-A1 Method of manufacturing glimepiride and the respective intermediate ZENTIVA, A.S. (CZ) 2007-03-08 US claimed
US-6358399-B1 HYDROCARBON STEAM-CRACKING EFFLUENT IS ABSORBED IN AN ABSORPTION COLUMN BY A COOLED SOLVENT; LIQUID PHASE IS RECOVERED AND HYDROGENATED; HYDROGENATION EFFLUENT IS DISTILLATED; SOLVENT IS COOLED AND RECYCLED; COLLECTING INSTITUTE FRANCAIS DU PETROLE (FR) 2002-03-19 US claimed
US-6340429-B1 Process and device for separating ethane and ethylene from a steam-cracking effluent by solvent absorption and hydrogenation of the solvent phase INSTITUT FRANCAIS DU PETROLE (FR) 2002-01-22 US claimed
EP-0135162-B1 TARTRIC ACID MONOESTERS OF OPTICALLY ACTIVE AMINOALCOHOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE Lindner, Wolfgang, Prof. Dr. (AT) 1990-04-04 EP claimed
EP-0135162-A2 Tartric acid monoesters of optically active aminoalcohols, process for their preparation and their use Lindner, Wolfgang, Prof. Dr. (AT) 1985-03-27 EP claimed
US-4126523-A Method and means for electrolytic precleaning of substrates and the electrodeposition of aluminum on said substrates ALUMATEC, INC. (US) 1978-11-21 US claimed
JP-9301894-A None JP disclosed
JP-61204616-A None JP disclosed
US-20240197923-A1 IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS INSTITUT PASTEUR (FR) 2024-06-20 US disclosed
US-3993683-A ANTITHROMBOTIC, ANTICHOLESTEREMICS, ANTICOAGULANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-11-23 US disclosed
US-3954734-A PENICILLIN AND CEPHALOSPORIN TYPE PARKE, DAVIS & COMPANY 1976-05-04 US disclosed
US-3933470-A Ester of (alkynyloxy)-, (alkenyloxy)-, and (cyanoalkoxy) carbanilic acids and their use as herbicides AMERICAN CYANAMID COMPANY (US) 1976-01-20 US disclosed
US-3931235-A FROM THE ALKALIMETAL SALT OF 4-HYDROXY-6-METHYL-2-PYRONE AND A THIOLSULFONATE THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070054954-A1 Method of manufacturing glimepiride and the respective intermediate DPP4, GLI2, GCG ACHE 907/4885TSHR 611/4885LMNA 3305/4885
US-20240197923-A1 IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS NISCH, HLCS, CYP3A5 ACHE 504/4885TSHR 3922/4885LMNA 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.