SCHEMBL480127

SCHEMBL480127

N#Cc1cc2ccc(O)cc2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 8/20 1.00
CA9 Q16790 2/20 1.00
MEN1 O00255 6/20 0.61
GLA P06280 6/20 0.61
KMT2A Q03164 6/20 0.61
GPR35 Q9HC97 2/20 0.59
HSD17B3 P37058 2/20 0.58
KDM4E B2RXH2 6/20 0.57
MAPT P10636 3/20 0.57
ESR2 Q92731 1/20 0.55
GAA P10253 4/20 0.54
S1PR4 O95977 2/20 0.54
S1PR1 P21453 2/20 0.54
PTGS1 P23219 1/20 0.54
ALDH1A1 P00352 4/20 0.53
HPGD P15428 3/20 0.53
NPSR1 Q6W5P4 2/20 0.53
NPC1 O15118 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
TDP1 Q9NUW8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745909 0.83 MIF (0.71) MIFCA9MEN1GLAKMT2A
SCHEMBL15842472 0.83 MIF (0.71) MIFCA9MEN1GLAKMT2A
SCHEMBL6379547 0.83 HSD17B3 (0.68) MIFCA9MEN1GLAKMT2A
SCHEMBL24715090 0.80 MIF (0.67) MIFCA9MEN1GLAKMT2A
SCHEMBL29943964 0.80 MIF (0.67) MIFCA9MEN1GLAKMT2A
SCHEMBL9635601 0.80 MIF (0.67) MIFCA9MEN1GLAKMT2A
SCHEMBL15842406 0.78 GPR35 (0.65) MIFCA9MEN1GLAKMT2A
SCHEMBL622794 0.77 KDM4E (0.64) MIFCA9MEN1GLAKMT2A
SCHEMBL5296804 0.77 HSD17B3 (0.68) MIFCA9MEN1GLAKMT2A
SCHEMBL1094715 0.76 GLA (1.00) MIFCA9MEN1GLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118843334-A Perovskite solar cell, preparation method thereof and power utilization device 宁德时代新能源科技股份有限公司 2024-10-25 CN claimed
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-23 US claimed
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377898-B1 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377904-B1 UREA BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
CN-117630356-A Method and reagent for detecting bacterial vesicle 南方医科大学南方医院 2024-03-01 CN claimed
CN-112322715-B Nucleic acid sequencing method 清华大学 2022-11-25 CN claimed
US-20220244266-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2022-08-04 US claimed
WO-2022105640-A1 NUCLEIC ACID SEQUENCING METHOD 清华大学 2022-05-27 WO claimed
EP-3997462-A1 ASSAYS FOR IMPROVING AUTOMATED ANTIMICROBIAL SUSCEPTIBILITY TESTING ACCURACY Selux Diagnostics Inc. (US) 2022-05-18 EP claimed
WO-2012168415-A1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2012-12-13 WO claimed
EP-2532753-A1 Method for detection of beta-D-glucuronidase Biosynth AG (CH) 2012-12-12 EP claimed
EP-2516666-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M Innovative Properties Company (US) 2012-10-31 EP claimed
US-20120252049-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US claimed
WO-2011087711-A1 METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO claimed
US-20100038632-A1 ELECTROLUMINESCENT DEVICE OLED-T LIMITED (GB) 2010-02-18 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
WO-1993016064-A1 COUMARIN DERIVATIVES AND THEIR ANALOGUES INHIBITING CELL PROLIFERATION AND TUMOUR GROWTH, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME BIOSIGNAL, Kutató-Fejleszto^' Kft. (HU) 1993-08-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 MIF 3154/4885CA9 185/4885MEN1 2391/4885
US-20220244266-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 MIF 3154/4885CA9 185/4885MEN1 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.