SCHEMBL4801310

SCHEMBL4801310

CC(=Cc1ccc(S(=O)(=O)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 4/20 0.67
AKR1C2 P52895 2/20 0.50
AKR1C1 Q04828 2/20 0.50
PTGS2 P35354 2/20 0.50
HDAC1 Q13547 1/20 0.50
HTR6 P50406 1/20 0.48
APEX1 P27695 3/20 0.47
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.44
TBXAS1 P24557 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5420947 0.88 AKR1C3 (0.55) AKR1C3AKR1C2AKR1C1PTGS2ALDH1A1
SCHEMBL5420950 0.88 AKR1C3 (0.55) AKR1C3AKR1C2AKR1C1PTGS2ALDH1A1
SCHEMBL8039241 0.83 ALDH1A1 (0.56) AKR1C2AKR1C1PTGS2HDAC1HTR6
SCHEMBL4803009 0.82 AKR1C3 (0.65) AKR1C3AKR1C2AKR1C1PTGS2
SCHEMBL8490337 0.82 AKR1C3 (0.65) AKR1C3AKR1C2AKR1C1PTGS2
SCHEMBL27792566 0.82 AKR1C3 (0.60) AKR1C3AKR1C2AKR1C1PTGS2HDAC1
SCHEMBL41906 0.81 AKR1C3 (1.00) AKR1C3AKR1C1APEX1ALDH1A1SMN1; SMN2
SCHEMBL581982 0.81 AKR1C3 (1.00) AKR1C3AKR1C1APEX1ALDH1A1SMN1; SMN2
SCHEMBL37034 0.81 AKR1C3 (1.00) AKR1C3AKR1C1APEX1ALDH1A1SMN1; SMN2
SCHEMBL16568719 0.81 AKR1C3 (1.00) AKR1C3AKR1C1APEX1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7416821-B2 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2008-08-26 US disclosed
EP-1743363-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FujiFilm Electronic Materials USA, Inc. (US) 2007-01-17 EP disclosed
US-20050238997-A1 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2005-10-27 US disclosed
WO-2005089150-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS USA INC. (US) 2005-09-29 WO disclosed