Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803009 | 1.00 | AKR1C3 (0.65) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL27792566 | 0.85 | AKR1C3 (0.60) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL2462983 | 0.84 | AKR1C3 (0.82) | AKR1C3 | |
| SCHEMBL2462984 | 0.84 | AKR1C3 (0.82) | AKR1C3 | |
| SCHEMBL396732 | 0.84 | AKR1C3 (0.58) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL9347806 | 0.84 | AKR1C3 (0.58) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL396731 | 0.84 | AKR1C3 (0.58) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL4801310 | 0.82 | AKR1C3 (0.67) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL397778 | 0.81 | AKR1C3 (0.55) | AKR1C3PTGS2AKR1C2AKR1C1 | |
| SCHEMBL397777 | 0.81 | AKR1C3 (0.55) | AKR1C3PTGS2AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976527-A | High surface area support having bound latex particles containing oxirane groups for immobilization of substances | SIOL, WERNER ROEHM GMBH CHEMISHE FABRIK (DE) | 1999-11-02 | — | — | US | disclosed |