E626

E626

SCHEMBL4801526

CC(C)[C@H](N)C(=O)O.Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.72
IMPDH2 P12268 7/20 0.67
IMPDH1 P20839 2/20 0.67
TAS1R3 Q7RTX0 2/20 0.66
TAS1R1 Q7RTX1 2/20 0.66
TGM2 P21980 1/20 0.65
HINT1 P49773 1/20 0.62
KRAS P01116 7/20 0.61
FUT5 Q11128 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E626 SCHEMBL15671022 0.93 NT5E (0.67) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL15671169 0.92 NT5E (0.62) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL13497991 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL20677331 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL21163348 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL9980018 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL21803790 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL18759049 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL20276926 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
E626 SCHEMBL18763818 0.91 NT5E (0.83) NT5EIMPDH2IMPDH1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7321626-B2 System and method for predictive motion estimation using a global motion predictor SHARP LABORATORIES OF AMERICA, INC. (US) 2008-01-22 US claimed
US-20040057520-A1 System and method for predictive motion estimation using a global motion predictor SHARP KABUSHIKI KAISHA (JP) 2004-03-25 US claimed
US-7321626-B2 System and method for predictive motion estimation using a global motion predictor SHARP LABORATORIES OF AMERICA, INC. (US) 2008-01-22 US disclosed
US-20040057520-A1 System and method for predictive motion estimation using a global motion predictor SHARP KABUSHIKI KAISHA (JP) 2004-03-25 US disclosed