Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17527894 | 0.95 | MAOA (0.43) | MAOAMAOBHTR2AHTR2CRIPK1 | |
| SCHEMBL7736449 | 0.90 | RIPK1 (0.36) | MAOAMAOBRIPK1P2RX7OPRM1 | |
| SCHEMBL8983091 | 0.90 | MAOA (0.38) | MAOAMAOBHTR2AHTR2CRIPK1 | |
| SCHEMBL7736446 | 0.90 | RIPK1 (0.36) | MAOAMAOBRIPK1P2RX7OPRM1 | |
| SCHEMBL8983100 | 0.90 | MAOA (0.38) | MAOAMAOBHTR2AHTR2CRIPK1 | |
| SCHEMBL7736441 | 0.90 | RIPK1 (0.36) | MAOAMAOBRIPK1P2RX7OPRM1 | |
| SCHEMBL10091238 | 0.88 | MAOA (0.40) | MAOAMAOBHTR2AHTR2CRIPK1 | |
| SCHEMBL10715641 | 0.88 | MAOA (0.51) | MAOAMAOBHTR2AHTR2C | |
| SCHEMBL9247392 | 0.87 | HTR2A (0.36) | MAOAMAOBHTR2AHTR2CRIPK1 | |
| SCHEMBL9247386 | 0.87 | HTR2A (0.36) | MAOAMAOBHTR2AHTR2CRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445818-B2 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20070275182-A1 | Matrix liquid crystal display | WEBER GEORG | 2007-11-29 | — | — | US | disclosed |
| US-7186447-B2 | Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity | MERCK PATENT GMBH (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20050196551-A1 | Matrix liquid crystal display | WEBER GEORG (DE) | 2005-09-08 | — | — | US | disclosed |
| US-6905740-B2 | The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. | MERCK PATENT GMBH (DE) | 2005-06-14 | — | — | US | disclosed |
| US-20030207046-A1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-11-06 | — | — | US | disclosed |
| US-6562419-B1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-05-13 | — | — | US | disclosed |
| US-6004479-A | FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS | MERCK KGAA (DE) | 1999-12-21 | — | — | US | disclosed |
| US-5519525-A | CONTAINING INTEGRATED NON-LINEAR ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-05-21 | — | — | US | disclosed |
| US-5378395-A | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-01-03 | — | — | US | disclosed |
| US-5236620-A | 2,3-DIFLUOROBENZENE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| US-5122295-A | Containing liquid crystal mixture with high resistivity | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-06-16 | — | — | US | disclosed |