Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10222197 | 0.83 | PPARG (0.58) | KDM4EMAOBPLA2G4BROCK1 | |
| SCHEMBL4145891 | 0.80 | LTA4H (0.56) | KDM4EALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL5348782 | 0.78 | ROCK1 (0.56) | KDM4EALDH1A1MAOBSIGMAR1PLA2G4B | |
| SCHEMBL4135562 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1PLA2G4BACHESMN1; SMN2 | |
| SCHEMBL13305516 | 0.76 | LTA4H (0.55) | KDM4EALDH1A1BCHEACHESSTR4 | |
| Hydrochloric Acid SCHEMBL4129206 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1PLA2G4BACHESMN1; SMN2 | |
| SCHEMBL25081992 | 0.75 | PLA2G4B (0.62) | PLA2G4BKMT2A | |
| SCHEMBL30278809 | 0.75 | PLA2G4B (0.62) | PLA2G4BKMT2A | |
| SCHEMBL23639968 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1TDP1MAOBBCHE | |
| SCHEMBL25081990 | 0.73 | PLA2G4B (0.68) | KDM4EALDH1A1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939202-A1 | NOVEL ADENINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-07-02 | — | — | EP | disclosed |