Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | HTR7 | P34969 | 6/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849595 | 0.90 | KDM1A (0.55) | LTA4HKDM4EHTR1AHTR7SIGMAR1 | |
| SCHEMBL13850499 | 0.84 | SMN1; SMN2 (0.52) | LTA4HKDM4EHTR1AHTR7SIGMAR1 | |
| SCHEMBL4629303 | 0.80 | KDM4E (0.67) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL4801766 | 0.80 | KDM4E (0.55) | KDM4ESIGMAR1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL980503 | 0.79 | KDM4E (0.65) | LTA4HKDM4EALDH1A1 | |
| SCHEMBL4802393 | 0.78 | CCR5 (0.50) | LTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5348782 | 0.78 | ROCK1 (0.56) | KDM4ESIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30696783 | 0.76 | EPHX2 (0.56) | LTA4HKDM4ESIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10222197 | 0.76 | PPARG (0.58) | KDM4E | |
| SCHEMBL14144084 | 0.76 | PLA2G4B (0.57) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118263-A1 | Novel Adenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1939202-A1 | NOVEL ADENINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118263-A1 | Novel Adenine Compound | ADORA1, ADORA2A, ADORA3 | LTA4H 1647/4885KDM4E 2809/4885HTR1A 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.