Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651203 | 0.98 | KDM4E (0.66) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL17949841 | 0.91 | KDM4E (0.60) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL14419047 | 0.90 | KDM4E (0.69) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL5651563 | 0.89 | KDM4E (0.68) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL10769714 | 0.88 | KDM4E (0.57) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL10766144 | 0.88 | KDM4E (0.57) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL8018518 | 0.88 | KDM4E (0.62) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL6136816 | 0.87 | KDM4E (0.73) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL10768477 | 0.87 | KDM4E (0.56) | KDM4EMEN1KMT2AMAPTUSP2 | |
| SCHEMBL6562559 | 0.85 | KDM4E (0.54) | KDM4EMEN1KMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | claimed |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-7204857-B1 | Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL S.A. (FR) | 2007-04-17 | — | — | US | claimed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| US-9115464-B2 | Particles for electrophoretic displays | MERCK PATENT GMBH (DE) | 2015-08-25 | — | — | US | disclosed |
| WO-2015122567-A1 | NOVEL DYE COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION COMPRISING SAME, AND COLOUR FILTER | 제일모직 주식회사 | 2015-08-20 | — | — | WO | disclosed |
| US-20120041165-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20110306742-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-12-15 | — | — | US | disclosed |
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | disclosed |
| US-20070207331-A1 | Azo compounds and coating compositions containing the azo compounds | EASTMAN CHEMICAL COMPANY | 2007-09-06 | — | — | US | disclosed |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | disclosed |
| US-4224025-A | Process for the dyeing and printing of paper materials in different hues using a single coupling component | CIBA-GEIGY CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | disclosed |
| US-4102880-A | COLORFASTNESS, BRILLIANT GREENISH-YELLOW | CIBA-GEIGY CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4097475-A | FOR POLYESTERS AND BLENDS WITH CELLULOSE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4032532-A | AZO DYES | SANDOZ LTD. (CH) | 1977-06-28 | — | — | US | disclosed |
| US-4015934-A | EXHAUST DYEING; DISPERSE, MONOAZO DYES | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3932122-A | COLORING POLYESTER TEXTILES | CIBA-GEIGY AG (CH) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207331-A1 | Azo compounds and coating compositions containing the azo compounds | EED, RARG, MLLT1 | KDM4E 354/4885MEN1 2529/4885KMT2A 574/4885 |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | KDM4E 440/4885MEN1 2976/4885KMT2A 927/4885 |
| US-20110306742-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | RAB5IF, IK, SELP | KDM4E 3448/4885MEN1 4319/4885KMT2A 4136/4885 |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | KRT18, KIT, CKMT1A; CKMT1B | KDM4E 1324/4885MEN1 3980/4885KMT2A 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.