Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366365 | 0.89 | MAPT (0.58) | KMT2AMAPTKCNN4CYP2C9HTT | |
| Hydrochloric Acid SCHEMBL23198120 | 0.87 | MAPT (0.56) | KMT2AMAPTKCNN4CYP2C9HTT | |
| SCHEMBL9142680 | 0.86 | CYP2C9 (0.64) | KMT2AMAPTKCNN4CYP2C9HTT | |
| SCHEMBL9142699 | 0.86 | CYP2C9 (0.64) | KMT2AMAPTKCNN4CYP2C9HTT | |
| Ethane SCHEMBL3002447 | 0.85 | MAPT (0.59) | KMT2AMAPTKCNN4CYP2C9HTT | |
| SCHEMBL4800452 | 0.78 | MAPT (0.57) | KMT2AMAPTKCNN4HTTCYP2D6 | |
| SCHEMBL2319756 | 0.78 | KMT2A (0.54) | KMT2AMAPTKIF11MEN1KCNH2 | |
| SCHEMBL8506184 | 0.77 | KCNN4 (0.46) | KMT2AMAPTKCNN4CYP2C9HTT | |
| SCHEMBL6871299 | 0.77 | CYP19A1 (0.54) | KMT2AHTTLMNAMEN1TSHR | |
| SCHEMBL8218323 | 0.76 | TSHR (0.48) | KMT2AMAPTKCNN4CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103184054-B | Crystal aligning agent, liquid crystal orienting film, liquid crystal display cells, polymkeric substance and compound | JSR CO., LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-103184054-A | Liquid crystal alignment agent, liquid crystal alignment film, liquid crystal display element, polymer and compound | JSR K K | 2013-07-03 | — | — | CN | disclosed |
| US-7414048-B2 | 4,5-dihydro-isoxazole derivatives and their pharmaceutical use | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-08-19 | — | — | US | disclosed |
| EP-1119568-B1 | 4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | JANSSEN PHARMACEUTICA NV (BE) | 2004-02-18 | — | — | EP | disclosed |
| US-20040019059-A1 | 4,5-Dihydro-isoxazole derivatives and their pharmaceutical use | FREYNE EDDY JEAN EDGARD (BE) | 2004-01-29 | — | — | US | disclosed |
| US-6583141-B1 | T cell mediated rheumatic diseases | JANSSEN PHARMACEUTICA, N.V. (BE) | 2003-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019059-A1 | 4,5-Dihydro-isoxazole derivatives and their pharmaceutical use | CBR1, CYP2D6, HSD3B1 | KMT2A 3726/4885MAPT 4752/4885KCNN4 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.