SCHEMBL366365

SCHEMBL366365

NC(=O)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
KMT2A Q03164 1/20 0.58
KCNN4 O15554 9/20 0.50
CYP2C9 P11712 1/20 0.50
HTT P42858 3/20 0.47
CYP1A2 P05177 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23198120 0.98 MAPT (0.56) MAPTKMT2AKCNN4CYP2C9HTT
Ethane SCHEMBL3002447 0.95 MAPT (0.59) MAPTKMT2AKCNN4CYP2C9HTT
SCHEMBL4801886 0.89 KMT2A (0.48) MAPTKMT2AKCNN4CYP2C9HTT
SCHEMBL16162191 0.83 LMNA (0.51) MAPTKMT2AKCNN4CYP2C9POLB
SCHEMBL2319756 0.83 KMT2A (0.54) MAPTKMT2APARP1
SCHEMBL8506184 0.82 KCNN4 (0.46) MAPTKMT2AKCNN4CYP2C9HTT
SCHEMBL6871299 0.82 CYP19A1 (0.54) KMT2AHTTL3MBTL1POLBTSHR
SCHEMBL12801471 0.82 MAPT (0.42) MAPTKMT2AKCNN4CYP2C9HTT
SCHEMBL16397521 0.80 MAPT (0.48) MAPTKMT2AKCNN4CYP2C9HTT
Benzylic Acid SCHEMBL21434289 0.80 CYP2C9 (0.68) MAPTKMT2AKCNN4CYP2C9HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0098743-A1 Phenyl alpha-acyloxyacetamide derivates and their therapeutic use Yu, Ruey J., Dr. (US) 1984-01-18 EP claimed
US-12601992-B2 Developing roller, process cartridge, electrophotographic image forming apparatus, and electrophotographic image forming system Konica Minolta, Inc. (JP) 2026-04-14 US disclosed
US-20240353777-A1 DEVELOPING ROLLER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2024-10-24 US disclosed
CN-118043397-A Three-dimensional printing 惠普发展公司,有限责任合伙企业 2024-05-14 CN disclosed
CN-117865847-A Ligand compound containing benzidine group, metal complex, metal supported catalyst and application thereof 合肥中科科乐新材料有限责任公司 2024-04-12 CN disclosed
CN-114366858-B Tracheal catheter with antibacterial and phlegm-thrombus-preventing functions and preparation method thereof 东华大学 2023-07-25 CN disclosed
CN-106659697-B Compounds as antituberculosis agents 斯菲叶尔制药私有公司 2022-03-29 CN disclosed
WO-2020244968-A1 FUNGICIDAL N-(PYRID-3-YL)CARBOXAMIDES BASF SE (DE) 2020-12-10 WO disclosed
US-9771345-B2 Coferons and methods of making and using them CORNELL UNIVERSITY (US) 2017-09-26 US disclosed
US-9771345-B2 Coferons and methods of making and using them CORNELL UNIVERSITY (US) 2017-09-26 US disclosed
CN-101385105-A Capacitor and method for fabricating the capacitor SHINETSU POLYMER CO (JP) 2009-03-11 CN disclosed
CN-101379138-A Conductive polymer solution, conductive coating film, capacitor and method for producing same SHINETSU POLYMER CO (JP) 2009-03-04 CN disclosed
EP-2004643-A1 ORGANIC COMPOUNDS Novartis AG (CH) 2008-12-24 EP disclosed
EP-1993113-A1 CAPACITOR AND METHOD FOR FABRICATING THE CAPACITOR SHIN-ETSU POLYMER CO., LTD. (JP) 2008-11-19 EP disclosed
WO-2007113226-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2007-10-11 WO disclosed
EP-0383256-A2 A novel substituted-acetamide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-08-22 EP disclosed
EP-0098743-B1 PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE Yu, Ruey J., Dr. (US) 1988-09-28 EP disclosed
US-4518789-A Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use YU RUEY J 1985-05-21 US disclosed
EP-0098743-A1 Phenyl alpha-acyloxyacetamide derivates and their therapeutic use Yu, Ruey J., Dr. (US) 1984-01-18 EP disclosed
US-4353922-A DERIVATIVES OF 7-AZABICYCLO(2,2,1)HEPTANE SYNTEX (U.S.A.) INC. (US) 1982-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12601992-B2 Developing roller, process cartridge, electrophotographic image forming apparatus, and electrophotographic image forming system MARK4, MAP1LC3B, MAP1LC3A MAPT 175/4885KMT2A 109/4885KCNN4 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.