Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.76 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797786 | 0.86 | AHR (1.00) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL30307425 | 0.86 | AHR (1.00) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL30288215 | 0.86 | AHR (1.00) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL25877004 | 0.85 | AHR (0.70) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL12471024 | 0.83 | AHR (0.53) | AHRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24140755 | 0.83 | AHR (0.67) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL25876975 | 0.83 | AHR (0.67) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL4806255 | 0.83 | SMN1; SMN2 (0.67) | AHRF2RL3APPKDM4ESMN1; SMN2 | |
| SCHEMBL12471049 | 0.83 | AHR (0.53) | AHRKDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4803129 | 0.83 | AHR (0.79) | AHRF2RL3APPKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384966-B2 | 2-arylbenzothiazole derivatives | PHARMINXO LIMITED (GB) | 2008-06-10 | — | — | US | disclosed |
| US-20060063816-A1 | 2-Arylbenzothiazole derivatives | STEVENS MALCOLM F G | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063816-A1 | 2-Arylbenzothiazole derivatives | CX3CR1, HCN2, CYBB | AHR 60/4885F2RL3 3432/4885APP 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.